دانلود مقاله Histopathological changes in liver and kidneys of cyprinid fishes due to water pollution in Kor River, Fars Province, Iran
سال انتشار: ۱۳۸۷
محل انتشار: اولین کنگره بین المللی مدیریت بهداشتی و بیماریهای آبزیان
تعداد صفحات: ۱
A Khodakaram-Tafti – Departments of Pathology and Physiology, School of Veterinary Medicine, Shiraz University, Shiraz, Iran
M Taherianfard –
A Zohrian –
Method & Materials: In this study, Kor River was divided into three zones, as upper zone (Doroodzan dam zone), mid zone (Band-e- Amir village) and lower zone (korbal village). From each zone, 10 fish were caught and after necropsy, samples of liver and kidneys were fixed in 10% buffered formalin, embedded in paraffin, sectioned at 5 μm, stained with hematoxylin and eosin (HE) and examined by light microscopy.
Results & Conclusion: Histopathological changes in the liver were include congestion, cell swelling and vacuolar degeneration of hepatocytes, bile stagnation with canaliculi dilatation, hemosiderosis and deposit of hemosiderin pigment in the cytoplasm of kupffer cells, prevascular oedema and remarkable increase in the size and number of melano-macrophage centres; and in the kidneys, congestion, cell swelling and vacuolar degeneration of epithelial cells of tubules, oedema, hemorrhage, acute tubular necrosis, deposition of oxalate crystals and hyaline casts within tubules lumen. In these tissues, maximum histopathological changes were found in fish caught from mid zone of Kor River. According to the present results, it seems that water contamination in Kor River lead to induce microscopic changes in the liver and kidneys of fish.