دانلود مقاله Micro and nanoparticles Formation, Characterization and Application of Biodegradable Polyurethane for Controlled Released of Theophilline
سال انتشار: ۱۳۸۶
محل انتشار: دومین کنفرانس نانوساختارها
تعداد صفحات: ۲
M Mahmoudi – Institute for nanoscience and Nanotechnology, Sharif University of Technology
Theophylline was encapsulated in polyurethane prepared with Hexamethylenediisocynate (HMDI), Polycaprolactone (PCL) (MW=530) and Starch as polyols and Butone diol as chain extender. Polyurethane micro and nanospheres were prepared in two reactors which includes polyurethane preparation and micro and nanospheres formation, respectively. PCL/starch, HMDI and theopylline were mixed in the first reactor and then transferred to the aqueous medium (moving at 5000 rpm) of the second reactor.